Based on dialectical relationship between active and toxic ingredient to discuss new research thinking
- VernacularTitle:基于药、毒效成分辨证关系探讨有毒中药研究思路
- Author:
Hongyu ZHAO
;
Chunxiang ZHOU
- Publication Type:Journal Article
- Keywords:
toxic Chinese materia medica;
active ingredients;
toxic ingredients;
dialectical relationship;
research thinking
- From:
Chinese Traditional and Herbal Drugs
1994;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
The toxic Chinese materia medicia (CMM) has been considered as the combination of active ingredients and toxic ingredients. After reviewing on the theory of traditional Chinese medicine (TCM),combined with clinical and experimental researches,it was found that the two kinds of ingredients have dialectical relationship,they were manifested with "double-side" or "multi-surface" ,even could change into each other. Based on the above understanding,the new research mehods were proposed as follows:Evaluating toxicity of toxic CMM under the physiological and pathological states; Establishing its drug-nature and toxicity under the different pathological states; Focusing on different pathological states to establish the best combination of active and toxic ingredients; Exploring the transitional mechanism of the active and toxic ingredients.