Magnetic resonance spectroscopy evolution of brain ischemic penumbra in acute stage
- VernacularTitle:急性脑梗死缺血半暗带演变的磁共振波谱分析
- Author:
Ke QIN
- Publication Type:Journal Article
- Keywords:
Hydrogen proton magnetic resonance spectroscopy(1HMRS);
Acute cerebral infarction;
Isehemic penumbra;
Evolution
- From:
Journal of Chongqing Medical University
2007;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the changes of metabolites in the acute cerebral infarction by 1HMRS and to identify the pre-sent time window and range of ischemic penumbra.Methods:Forty-four patients with hyperacute and acute cerebral infarctions were divided into five groups according to the time of attack.The normal side was taken as control.Routine MRI,DWI and PRESS multiple voxel acquisition were performed in all cases.The metabolites of NAA,Cr,Lac and the ratio of NAA/Cr and Lac/Cr were analyzed.Statistical analysis was performed by SPSS 13.0 software package,t-test and ANOVA analysis were used to detect the significance within each group and among different groups.Results:(1)Compared with counterpart,the decrease of NAA/Cr and the increase of Lac/Cr in cehtral region and posterior marginal region were significant inCompared with counterpart,the decrease of NAA and the increase of Lac in the acute lesions were significant(P0.05).But the significant differences were shown over time(P
