Regulation Effect of Shengmai Injection on T Helper Cells Balance in Patients with Graves Disease
- VernacularTitle:生脉注射液对Graves病Th1/Th2细胞平衡的调节作用
- Author:
Shumin MU
;
Yanhua CHEN
- Publication Type:Journal Article
- Keywords:
Shengmai Injection;
Graves disease;
Th1/Th2 cells;
cytokine
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of Th1/Th2 cytokine in patients with Graves disease(GD) and the regulation effect of Shengmai Injection on its balance.Methods The patients with GD were randomly divided into 2 groups,the Shengmai treated group and the Methimazole treated group,30 cases per group and 30 healthy subjects were enrolled in this study.The serum concentrations of their Th1 cytokine(IFN-?) and Th2 cytokine(IL-10) were assayed by ELISA before and after treatment.Results The serum levels of INF-? and IL-10 in patients with GD were significant higher and the ratio of INF-?/IL-10 were significant lower than healthy subjects(P
