Effect of Shendi Tangmaining on Immune System in Diabetic Rats
- VernacularTitle:参地糖脉宁对糖尿病大鼠免疫系统的影响
- Author:
Ping HE
;
Xueliang ZHANG
;
Xueguang ZHANG
- Publication Type:Journal Article
- Keywords:
diabetes;
aspirin;
Shendi Tangmaining;
TNF-?;
IL-6;
rat
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of Shendi Tangmaining on T cells and cytokines(TNF-?,IL-6) and the index of immune organ in diabetic rats.Methods Forty eight male SD rats were divided into diabetic group(DM group),aspirin interventing diabetic group(AD group),Shendi Tangmaining interventing diabetic group(SD group),control group(NC group).The count of CD3+,CD4+,CD8+ T cell in peripheral boold was detected with flow cytometry(FCM).TNF-? and IL-6 were analyzed with enzyme-linked immunosorbent assay(ELISA).The index of the thymus was measured.Results CD3+,CD4+,CD8+ T cell count and thymus index in DM group were significantly lower than in NC group(P
