Effects of Naoluoxintong on Neural Epithelium Stem Cell Protein Nestin Expressed of Cerebral Ischemia Reperfusion Rats
- VernacularTitle:脑络欣通对局灶性脑缺血再灌注大鼠神经上皮干细胞蛋白巢蛋白表达的影响
- Author:
Yenong CHEN
;
Jian WANG
;
Wei TANG
- Publication Type:Journal Article
- Keywords:
Naoluoxintong;
local cerebral ischemia-reperfusion;
neural stem cells;
Nestin proliferation
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of Naoluoxintong which is representative prescription of supplementing Qi and activating blood therapy(Yiqihuoxue),the prescription of supplementing Qi therapy(Yiqi) and the prescription of activating blood therapy(Huoxue) on local cerebral ischemia-reperfusion injury rats.To observe the changes of neural stem cells(NSCs) and correlated SVZ factors.Methods Models of local cerebral ischemia-reperfusion were established by thread-occluding the MCA.The time points were observed at 1,3,7 d after reperfusion following 2 h of MCAO respectively.The expression levels of Nestin were measured by immunohistochemical staining.Results The expression of Nestin of treatment groups increased significantly compared with model group at 7 d(P
