Therapeutic Effect of Benazepril Combination with Valsartan in Treatment of Chronic Kidney Patients with Proteinuria and Hypertension
- VernacularTitle:贝那普利与缬沙坦治疗慢性肾病蛋白尿及高血压
- Author:
Xing FAN
;
Tianbiao LAN
;
Xu WANG
- Publication Type:Journal Article
- Keywords:
Benazepril;
Valsartan;
Hypertension;
Proteinuria
- From:
Chinese Journal of Pharmacoepidemiology
2007;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the clinical efficacy of benazepril in combination with valsartan in treating chronic kidney patients with proteinuria and hypertension.Method:75 chronic kidney patients were divided into benazepril group(n=28)and valsartan group(n=26)and combination treatment group(n=21).The changes of 24 hours urinary protein excretion and blood pressure and serum BUN and SCr were observed before the treatment and 4 and 8 weeks after it. Result:The 24 hours urinary protein excretion and blood pressure in all the groups showed significant decreases after the treatment(P0.05),but the levels of SUA were significantly lower in the valsartan group and combination treatment group than those in the benazepril group(P
