THE EXPRESSION OF HISTAMINE IN THE CARDIAC SYMPATHETIC FIBERS FROM THE GUINEA PIG SUPERIOR CERVICAL GANGLION
- VernacularTitle:组胺在豚鼠颈上神经节投射到心脏交感神经纤维中的表达
- Author:
Jing HU
;
Mingkai LI
;
Yuanqiang ZHANG
;
Gonghao HE
;
Xiaoxing LUO
- Publication Type:Journal Article
- Keywords:
Histamine;
Norepinephrine;
Sympathetic nerve;
Superior cervical ganglion;
BDA anterograde tracing;
Immunofluorescence;
Guinea pig
- From:
Acta Anatomica Sinica
2002;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of histamine in the cardiac sympathetic fibers from the guinea pig superior cervical ganglion and its coexistence with norepinephrine so as to provide morphological evidence for histamine as a cardiac sympathetic neurotransmitter.Methods Biotinylated dextranamine(BDA) anterograde tracing and immunofluorescence histochemical staining for histamine/norepinephrine were applied.Results After injection of BDA into the superior cervical ganglion,BDA labeled sympathetic fibers in the left and right atria and ventricle were observed.Meanwhile,the tracing fibers proved histamine-like immunoreactive or both histamine and norepinephrine-like immunoreactive.Conclusion Histamine is expressed in the cardiac sympathetic fibers from the guinea pig superior cervical ganglion and coexisted with norepinephrine.
