Theophylline,prednisone acetate and dexamethasone acetate illegally mixed into traditional Chinese medicinal preparation for antitussive and antiasthmastics by UPLC-MS
- VernacularTitle:UPLC-MS法检测止咳平喘制剂中非法添加茶碱、醋酸泼尼松、醋酸地塞米松
- Author:
Cuiying ZHANG
;
Zhenguo LI
;
Jinling XU
- Publication Type:Journal Article
- Keywords:
UPLC-MS;
antitussive and antiasthmastics;
theophylline;
prednisone acetate;
dexamethasone acetate
- From:
Chinese Traditional Patent Medicine
1992;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To establish a quick,accurate,sensitive method for analysis of theophylline,prednisone acetate and dexamethasone acetate illegally added into traditional Chinese medicinal preparation for antitussive and antiasthmastics by UPLC-MS. METHODS: The UPLC-MS/MS method was used.Electrospay ionization(ESI) source was applied and operated in the positive and negative ion mode.Theophylline,prednisone acetate and dexamethasone acetate illegally added into traditional Chinese medicinal preparations were identified. RESULTS: Both theophylline and prednisone acetate were found in formulations. CONCLUSION: The method is selective and sensitive and can be used to detect the theophylline,prednisone acetate and dexamethasone acetate illegally added into traditional Chinese medicinal preparations.
