Correlation of Traditional Chinese Medical Syndrome Patterns with Endothelial Damage,Inflammation and Platelet Activation in Patients with Coronary Heart Disease
- VernacularTitle:冠心病中医辨证分型与内皮损伤、炎症反应及血小板活化的相关性研究
- Author:
Weiping LONG
;
Lei SHI
;
Aihuan WEI
;
Jianyi YANG
- Publication Type:Journal Article
- Keywords:
CORONARY DISEASE/pathogenesis(TCM);
ENDOTHELIAL DAMAGE;
INFLAMMATION;
PLATELET ACTIVATION
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective The differences of von Willebrand factor(vWF),hypersensitive C-reactive protein(hs-CRP) and soluble P-selectin CD62P were observed in coronary heart disease(CHD) patients with different syndrome patterns,and the correlation of traditional Chinese medical(TCM) syndrome patterns with endothelial damage,inflammation and platelet activation in CHD patients was investigated.Methods One hundred and eighty-six CHD patients were differentiated as the syndromes of blockage of heart-blood-stasis,phlegm blocking heart vessels,deficiency of heart and kidney yin,deficiency of both yin and Qi,and deficiency of yang and Qi.Thirty healthy volunteers served as normal control.The blood levels of vWF,hs-CRP and CD62P were detected in the CHD patients and the normal controls.Results Blood vWF level in CHD patients was higher than that in the normal controls(P0.05).Blood CD62P in the syndrome pattern of deficiency of yang and Qi was higher than the other patterns(P
