Effect of Coprinus comatus on Small Intestinal Propulsion and Gastric Emptying Function in Mice
- VernacularTitle:鸡腿菇对小鼠小肠推进、胃排空功能的影响
- Author:
Yingming WU
;
Qiaowan LIN
;
Yanqiong ZENG
;
Chunmei WU
;
Aiyu ZHU
- Publication Type:Journal Article
- Keywords:
COPRINUS COMATUS/pharmacology;
GASTROINTESTINAL FUNCTION/drug effects;
DISEASE MODELS,ANIMAL;
MICE
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of extract of Coprinus comatus on small intestinal propulsion and gastric emptying function in mice.Methods Effect of extract of Coprinus comatus at different doses on small intestinal propulsion and gastric emptying function was observed in normal mice,neostigmine-load mice and epinephrine-load mice by charcoal powder method and by modified phenol red method respectively.Results The small intestinal propulsion of normal mice was promoted by the extract of Coprinus comatus at the doses of 3.0,6.0,9.0 and 12.0 g/kg,and the gastric emptying function of normal mice was promoted by the extract of Coprinus comatus at the doses of 1.5,3.0,6.0,9.0 and 12.0 g/kg,the difference being significant as compared with the normal group (P
