Histopathological change of the fragrant pig skin induceced by focus ultrasound repetition irradiation
- VernacularTitle:聚焦超声对香猪皮肤重复损伤的组织病理学变化的研究
- Author:
Qing XIAO
- Publication Type:Journal Article
- Keywords:
Ultrasound;
Repetition;
Postherpetic neuralgia
- From:
Journal of Chongqing Medical University
2007;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the histopathological change of the fragrant pig skin induced by focus ultrasound repetition irradiation to offer experiment basis for the safety and effectivessness of clinically treating postherpetic neuralgia(PHN) by repetition irradiation.Methods:The pig skin was irradiated once every other day,altogether three,with irradiation power as 2W,and frequency as 10.06MHz,The skin change was observed under light microscope and electron microscope.Results:Hyperemia and edema in irradiation area after irradiation were observed instantly to the eye;Under light microscope there were hyperemia and edema in epidermis,angiotelectasis and inflammatory infiltrating,and find coagulative necrosis in slice was not observed.Under electron microscope,instantly after ultrasound irradiation every other day,endothelial cell of blood vessel can be found mitochondria swelling and more micropinocytotic vesicles,mitochondria swelling and rough endoplasmic reticulum dilatation were noted for in fibroblasts,and mitochondfia swelling for nerve fibre.Conclusions:(1)There is reversibile lesion in epidermis under this dose of ultrasound.(2)Skins don’t accumulate lesion every other day after irradiation repeatly .which illustrates that it is effective and safe to treat postherpetic neuralgia by ultrasound irradiation repeatly.
