Effect of Rheum emodi Wall on express level of TNF-?、IL-1? and IL-6 on acute ischemic stroke at high altitude
- VernacularTitle:藏边大黄对高原急性脑梗死患者的疗效及其血清TNF-?、IL-1?和IL-6含量的影响
- Author:
Zhiqing LIU
;
Aiqin ZHU
;
Meihua YU
- Publication Type:Journal Article
- Keywords:
Rheum emodi Wall;
TNF-?、IL-1?and IL-6;
acute ischemic stroke;
altitude
- From:
Chinese Traditional Patent Medicine
1992;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To observe the effect of Rheum emodi Wall on expess level of TNF-?、IL-1? and IL-6 on acute ischemic stroke(ACI)at high altitude. METHODS: 65 patients aith ACI at high altitude(2 260 m)were randomly divided into treatment group(34) and control groups(31).both groups received danshen-safflower injection.Meanwhile treatment group took Rheum emodi decoction orally for 4 weeks,while control group doesn't.Serum levels of TNF-?、IL-1? and IL-6 were measured by radioimmumoassay. RESULTS: The treatment group showed much higher rates of improvement than control group(88.24%;70.97%)after weeks.Serum levels of TNF-?、IL-1? and IL-6 decreased significantly in patients with ACI at treatment group as compared with those of control group. CONCLUSION: Rheum emodi Wall can improve the nervous function of ACI by reducing TNF-?、IL-1? and IL-6 content in serun.
