Development and Design of Diffusion Optical Tomography System
- VernacularTitle:漫射光学断层成像系统的研究与设计
- Author:
Huacheng FENG
;
Jing BAI
- Publication Type:Journal Article
- Keywords:
diffusion optical tomography;
optical imaging;
image reconstruction;
absorption coefficient
- From:Space Medicine & Medical Engineering
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To design and establish a set of diffusion optical tomography(DOT) system.Methods Near-infrared(NIR) laser was employed as the light source and only one photomultiplier tube(PMT) as the detector.An optical multiplexer was used to alter the detector channels.The 32 channels of the system,which are consisted of 16 launch channels and 16 detector channels,worked under the continuous-wave(CW) model and were used to acquire 256 boundary data.Results Experiments were performed based on the proposed imaging system.The intralipid was used as the tissue-like medium and the India ink as the absorber.Two sets of data on the boundary were sampled,respectively,before and after the absorber was embedded inside the tissue-like medium.The two sets of data were normalized and then used to reconstruct the absorption coefficient distribution.The recovered image reflected the real location and size of the absorber.Conclusion The proposed imaging platform can image the tissue optical parameters effectively.However the resolution of the reconstructed image was not high because the inverse problem was gravely underdetermined and the noise was not considered in the reconstruction algorithm.The recovered result in the next generation system could be improved by making more use of prior information and enhancing the performance of the system.
