Appilcation value and clinical curative effectiveness of ethanol in transcatheter arterial embolization for hepatocllular carcinoma(HCC) with portal vein tumor thrombus
- VernacularTitle:无水乙醇在原发性肝癌合并门静脉癌栓经导管动脉栓塞术中的应用价值
- Author:
Xiaoping LUO
- Publication Type:Journal Article
- Keywords:
Ethanol;
Hepatocellular carcinoma;
Portal vein;
Tumor thrombus;
Embolization
- From:
Journal of Chongqing Medical University
2007;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To retrospectively study the effect and curative effectiveness of ethanol in treating HCC with portal vein tumor thrombus(PVVT) through transcatheter fed arterial super selective infusion and super selective arterial embolization of main tumor,appraise the effect of ethanol in local treatment,in order to improve the clinical curative effects on the patients. Methods:The data of study from 86 cases of HCC with PVVT in our hospital between 2001~2004 year,to the fed artery of portal vein tumor thrombus super selective infusion ethanol or ethanol and gelfoam or ethanol and lipiodol,also through transcatheter super selective embolizing the fed arterys of main tumors including TACE or ethanol and lipiodol in 86 cases HCC. The course of observation was between 2001 and 2007year. Results:The super selective fed arterial embolization of PVVT and main tumors were successful in all cases;After treatment,ascites disappeared or obviously reduced in 66.3%(57/86) of cases,reduce in 23.2%(20/86),did not reduce in 10.5%(9/86);After 7~10d,hepatic function obviously improve or improve in 71%(61/86),did not obviously change in 11.6%(10/86),lowered in 6%(5/86),with no obvious lowering of hepatic function or hepatic function failure.The survival rates at 3,6,12,24,36months were 97.7%(84/86),95.5%(82/86),72.7%(62/86),47.7%(41/86) and 16.3%(14/86) respectively. Conclusion:The therapy of ethanol through catheter super selective PVVT fed arterial infusion is safe and effective,combined with super selective TAE or TACE to the fed artery of main tumor,could obviously improve the quality of life of the patients and could improve the survival rate.
