Determination of Bacterial Endotoxin in Maodongqing Compound Injection by Kine tic Turbidimetric Assay
- VernacularTitle:动态浊度法测定复方毛冬青注射液中的细菌内毒素含量
- Author:
Yi ZHUO
;
Yilu CHEN
;
Xiaolei SUN
- Publication Type:Journal Article
- Keywords:
Maodongqing Compound Injection;
Turbidimetric-kinetic method;
Bacte rial endotoxin
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop an assay for determining bacterial endotoxin(BE T) content in Maodongqing Compound Injection (MCI). Methods The dilution radio o f Maodongqing Compound Injection was optimized and BET content was determined by turbidimetric kinetic method. Results Dilution ratio of Maodongqing Compound In jection at 1 ∶80 did not interfere with the Limulus test. The average recovery of BET was between 50 %and 200 %. Conclusion The method is proved to be accura te,sensitive and suitable for the determination of BET content in Maodongqing C ompound Injection.
