Fingerprint of Xiasangju Granules and its application in quality control
- VernacularTitle:夏桑菊颗粒指纹图谱的建立及其在质量控制中的应用
- Author:
Xuehong KE
;
Weiguang SUN
;
Jiangxiong YAO
;
Rufeng HUA
;
Jinfu CHEN
- Publication Type:Journal Article
- Keywords:
Xiasangju Granules;
HPLC;
fingerprint;
quality control
- From:
Chinese Traditional Patent Medicine
1992;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To establish an effective and convenient method for applying HPLC fingerprints to quality control in the production of Xiasangju Granules(Spica prunellae,Folium mori,Flos chrysanthemi). METHODS: Komasil Sunfrie C_(18)(150 mm?4.6 mm,5 ?m) analytical column was used and eluted with a gradient program consisted of phase A(1% acetic acid) and phase B(methanol) and detected at 290 nm.The fingerprints of aqueous extract,alcohol-precipitated extract,concentrate and finished product were compared with. RESULTS: The fingerprint method for Xiasangju Granules was established.The similarity among 10 batches of Xiasangju Granules was no less than 0.970.The difference between extracts and finished product of Xiasangju Granules was obvious. CONCLUSION: This validated method is available for quality evaluation and quality control in Xiasangju Granule's production.
