Effect of Traditional Chinese Herb Fumigation and Steaming on IL-1? in Serum and Joint of AA Model Rats
- VernacularTitle:中药熏蒸对佐剂型关节炎大鼠血液、关节中白细胞介素-1?的影响
- Author:
Jidi LU
;
Ying SHEN
- Publication Type:Journal Article
- Keywords:
Chinese herb fumigation and steaming;
rat;
adjuvant arthritis;
IL-1?
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study traditional Chinese herb fumigation and steaming in treating AA model rats and the change of IL-1? in serum and joint, and explore its mechanism. Method Fifty Wistar rats were randomly divided into normal group, model group, aqua group, high dose group, low dose group. Except normal group and the right foot of rats were injected CFA 0.1 mL to make AA model. Aqua group, high dose group and low dose group received steam treatment for 10 days. In the 21st day, the content of IL-1? in serum and the expression level in joint were detected. Results Traditional Chinese herb fumigation and steaming group had notable reduction the IL-1? content in serum and strong positive expression of IL-1? in joint than model group. Conclusion Traditional Chinese herb fumigation and steaming can down-regulate the level of IL-1? in serum and restrain IL-1? expression in joint.
