Effect of Ningchang Decoction on Anti-Oxidative Ability of Irritable Bowel Syndrome Rats
- VernacularTitle:宁肠汤对肠易激综合征大鼠抗氧化能力的影响
- Author:
Haiyun WANG
- Publication Type:Journal Article
- Keywords:
Ningchang Decoction;
stress;
irritable bowel syndrome;
free radical;
rat
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(07):-
- CountryChina
- Language:Chinese
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Abstract:
Objective To investigate the regulation of Ningchang Decoction on free radical of stressed irritable bowel syndrome (IBS) rats. Methods The stressed IBS model rats were made by chronic bandaged-stress and inserting the end. The rats were randomly divided into six groups: normal control group, model control group, positive control group, high dosage of Ningchang Decoction group, middle dosage of Ningchang Decoction group, low dosage of Ningchang Decoction group. Different treatment were given to each group by ig administration for 4 weeks. The contents of SOD, MDA and T-AOC in serum of stressed IBS rats were determined and the regulation of Ningchang Decoction on them were observed. Results Stress increased the content of MDA in serum and decreased the contents of SOD and T-AOC in serum (P
