Effects of Total Glucosides of Paeony Combined with Vitamin D_3 on Serum Levels of IFN-? and IL-10 in RA Patients
- VernacularTitle:白芍总苷联合维生素D_3对类风湿关节炎患者血清中IFN-?和IL-10的影响
- Author:
Ximin WANG
;
Wei LIU
- Publication Type:Journal Article
- Keywords:
total glucosides of paeony;
vitamin D3;
rheumatoid arthritis;
IFN-?;
IL-10
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the serum levels of IFN-? and IL-10 in RA patients before and after receiving total glucosides of paeony combined with vitamin D3 therapy respectively and to explore the immunology mechanism of treating RA. Methods The levels of IFN-? and IL-10 in serum were determined by Enzyme-Linked Immunosorbent Assay (ELISA). Meanwhile, the disease activity and therapeutic effect were estimated. Results The level of IFN-? was significantly higher than the healthy controls (P 0.05). The level of IFN-? was significantly decreased and IL-10 was remarkably increased after treated with TGP combined with vitamin D3 (P
