A Case of Congenital Self-Healing Reticulohistiocytosis.
- Author:
Taek Sun KIM
1
;
Chang Wan KIM
;
Eun Ryoung KIM
;
You Mee KANG
;
Kye Yong SONG
Author Information
1. Department of Pediatrics, Sung-Ae General Hospital, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Congenital self healing reticulohistiocytosis;
Langerhans cell;
Birbeck granule;
Laminated body
- MeSH:
Biopsy;
Eosinophils;
Humans;
Infant, Newborn;
Microscopy, Electron;
Muramidase;
Parturition;
S100 Proteins;
Skin
- From:Journal of the Korean Pediatric Society
1998;41(10):1424-1439
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Congenital self-healing reticulohistiocytosis (CSHR) is a rare variant of cutaneous reticulohistiocytosis. We report a newborn who had about 25 reddish brown papulonodular lesions on whole body at birth. No extracutaneous involvement was found. All skin lesions involuted within 4 months spontaneously. Biopsy of a skin lesion showed marked aggregated histiocytic infiltration with some eosinophils. S-100 protein and lysozyme were positive. Electron microscopy revealed numerous dense bodies, often with a myelin-like core and some Birbeck granules. We described a detailed clinical features of this case and reviewed the literatures.
