Middle and long-term follow-up of intracranial aneurysms treated with Matrix detachable coils
- VernacularTitle:第一代Matrix弹簧圈治疗颅内动脉瘤的安全性及中长期随访结果分析
- Author:
Xi WU
;
Jianmin LIU
;
Qinghai HUANG
;
Yi XU
- Publication Type:Journal Article
- Keywords:
Polyglycolic/polylactic acid-coated Matrix platinum coils;
Intracranial aneurysms;
Stent
- From:Journal of Interventional Radiology
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective This study was undertaken to evaluate the safety of the polyglycolic/polylactic acid(PGLA)-coated Matrix detachable coils(Matrix) and analyze factors which may relate to the recanalization rate of the Matrix coils in the treatment of intracranial aneurysms. Methods 75 patients underwent 79 aneurysm treatments with Matrix coils from May 2003 to July 2005 were retrospectively investigated.Morphological changes were compared postoperatively with last-follow-up digital subtraction angiography(DSA)by using the Raymond scale. We defined incomplete recanalization or stable aneurysms as uncured , while those of progressive occlusion or complete occlusion aneurysms demonstrated on the last-follow-up imagings as cured. We also utilized Cox model for analyzing the relationships between factors including age, gender, degree of aneurysmal occlusion, stenting, aneurysm neck size, aneurysm maximum size and Matrix coils length(%)and the long-term angiographic follow-up results. Results The correlative surgical complications rate with Matrix coils was 13.3%. The total rate of recanalization was 11.4%. Large aneurysms treated with combined stenting got 40% recanalization. No statistic relationships were shown between the factors forementioned and the recanalization rate, but progressive occlusion was observed in 11(61%)incompletely treated aneurysms. Conclusions Matrix detachable coil technique is safe for intracranial aneurysm and would further decrease the recurrence of large aneurysm with combination of stenting but long term efficacy needs further follow-up and large scale randomized control study.
