Preparation Technology of Volatile Oils Obtained from Asarum and Lily magnolia Complexed with ?-cyclodextrin and Hydroxypropyl-?-cyclodextrin and Its Impacts of Transdermal Absorption
- VernacularTitle:细辛、辛夷挥发油?-环糊精和HP-?-环糊精包合物的制备及其对透皮吸收的影响
- Author:
Rong MA
;
Liuqing DI
;
Xiaolin BI
- Publication Type:Journal Article
- Keywords:
asarum;
lily magnolia;
volatile oils;
?-cyclodextrin;
hydroxypropyl-?-cyclodextrin;
transdermal absorption
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the preparation of volatile oils obtained from asarum and lily magnolia complexed with ?-cyclodextrin and hydroxypropyl-?-cyclodextrin in Xuetie Dingchuan plaster,and to study its impacts of transdermal absorption.Methods The volatile oil was complexed with ?-cyclodextrin and hydroxypropyl-?-cyclodextrin.GC method was used in the determination of volatile oils complexed with ?-cyclodextrin and hydroxypropyl-?-cyclodextrin to investigate the impacts of transdermal absorption.Results The accumulation transmission of the volatile oils complexed with ?-cyclodextrin was superior to that with hydroxypropyl-?-cyclodextrin.Conclusion The inclusion of volatile oils with ?-cyclodextrin can enhance drug penetration via skin.
