The Protective Function of Ziyin Huoxue Jiedu Chinese Herbs on the Vascular Endothelial Cells Injured
- VernacularTitle:滋阴活血解毒中药对血管内皮细胞损伤的保护作用
- Author:
Yihui DENG
;
Dingxiang LI
;
Rong YU
- Publication Type:Journal Article
- Keywords:
Ziyin Huoxue Jiedu herbs;
vascular endothelial cells;
glucose;
insulin;
ox-LDL;
anti-thrombus function
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of Ziyin Huoxue Jiedu Chinese herbs(ZYHXJD) on vascular endothelial cells injured by glucose,insulin and low-density lipoprotein.Methods Human umbilical vein endothelial cell line ECV-304 was exposed to different concentration of glucose,insulin and oxidized low-density lipoprotein(Ox-LDL),and the effects of ZYHXJD on the injured vascular endothelial cells were investigated.The cells in each group were cultured for additional 48 h.And then,cell viability was examined,and the supernatants were used to determine the contents of tissue plaminogen activator(tPA),plasminogen activator inhibitor(PAI),and intercellular adhesion molecule-1(ICAM-1) respectively.Results The viability of the cells in the model group decreased markedly(P
