Effects of Rhodiola Herb on Behavior and the Expression of Bcl-2 and Bax Protein in the Hippocampus of Vascular Dementia Rats
- VernacularTitle:红景天对血管性痴呆大鼠行为学及海马CA_1区Bcl-2及Bax表达的影响
- Author:
Faming YANG
;
Lianling DONG
;
Juan CAO
- Publication Type:Journal Article
- Keywords:
Rhodiola herb;
vascular dementia;
cognitive functions;
rat;
Bcl-2;
Bax
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of Rhodiola herb on behavior and the expression of Bcl-2 and Bax protein in hippocamps of vascular dementia rat induced by chonic cerebral ischemia.And the protective effect of Rhodiola herb was studied.Methods VD model was formed by adopting the permanent occlusion of bilateral carotid arteries in Wistar rats to produce the forebrain ischemia.Cognitive ability of rats were studied with the Morris water maze.The expression of Bcl-2 and Bax protein in the hippocampus were determined with immunohistochemical staining.Results VD model may decrease cognitive ability(P
