Effect of matrine on signaling transduction pathway of JAK-STAT in SMMC-7721 cell line
- VernacularTitle:苦参碱对肝癌SMMC-7721细胞JAK-STAT信号通路的影响
- Author:
Fei YIN
;
Junyan ZHAO
;
Shukun YAO
- Publication Type:Journal Article
- Keywords:
matrine;
JAK-STAT pathway;
proliferation;
AG490
- From:
Chinese Traditional and Herbal Drugs
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). Conclusion Matrine could significantly down-regulate the mRNA expression of stat3 and stat5 and protein expression of STAT3 and STAT5 in SMMC-7721 cells. So matrine could inhibit the signaling transduction pathway of JAK-STAT and inhibit the proliferation of SMMC-7721 cells.
