Correlation between P-glycoprotein and CD44 in cancer
- VernacularTitle:P-糖蛋白与CD44在肿瘤中表达的相关性
- Author:
Weifeng KE
- Publication Type:Journal Article
- Keywords:
P-glycoprotein;
Antigens,CD44;
Drug resistance,neoplasm;
Neoplasm invasiveness;
Neoplasm metastasis
- From:
Journal of International Oncology
2008;35(7):489-490,493
- CountryChina
- Language:Chinese
-
Abstract:
P-glycoprotein(P-gp)and CD44 have been characterized and are known to be determinants of multidrug resistance(MDR)and cancer metastases.Recent researches suggest that there is a correlation between P-glycoprotein(MDR)and CD44(invasion and metastases).A better understanding of any relationship between drug resistance and tumor metastasis may lead to more effective tumor treatment.
