Assay of NSE concentration in serum and cerebrospinal fluid of patients with viral encephalitis and its clinical correlation
- VernacularTitle:病毒性脑炎患者血液和脑脊液NSE含量测定及其与临床的相关性研究
- Author:
Zhenhai WANG
- Publication Type:Journal Article
- Keywords:
Neuron-specific enolase;
Viral encephalitis;
Enzyme-linked immunosorbent assay
- From:
Journal of Chongqing Medical University
2008;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the changes of neuron-specific enolase(NSE)concentration in serum and cerebrospinal fluid from patients with acute and recovery viral encephalitis and to find out its correlation with anomaly electroencephalogram and low density focus volume in imageology. Methods:42 cases of patients with viral encephalitis were enrolled and 25 cases of health examinater or patients with operation of appendix or cholecyst were enrolled in control group.We measured the NSE concentration in cerebrospinal fluid and serum using enzyme-linked immunosorbent assay. Comparison analysis was performed by using a SPSS13.0 statistical package. Results:NSE concentration in serum and cerebrospinal fluid of patients with acute viral encephalitis was significantly higher than that of recoverys and control group(P
