Study of the Sea Buckthorn Procyanidins's (SBPC) potencional mechanisim against peptic ulcer
- VernacularTitle:沙棘原花青素抗胃溃疡作用机制的研究
- Author:
Guodong HUANG
;
Yuanhua HUANG
;
Daofu HUANG
;
Meizhen XIAO
;
Lijun TANG
;
Jun ZHAO
- Publication Type:Journal Article
- Keywords:
Sea Buckthorn Procyanidins(SBPC);
peptic ulcer;
hydrophobicity;
phosphatide R;
aninohexose;
ITF;
PS_2
- From:
Chinese Traditional Patent Medicine
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the potencional mechanism of Sea Buckthorn Procyanidins(SBPC) against peptic ulcer. METHODS: 72 gastric ulcer patients(final diagnosis by gasroscope),were randomly divided into two groups,including Sea Buckthorn Procyanidins(SBPC) treatment group(36 cases),and Ranitidine control group(36 cases),among them,50 Hp-positive PU patients were confirmed by endoscopy,histological instection,urease test.Normal group was 12 cases.Detection on Biospy specimens of gastric mucosa was used to observe the change of ITF for Immunohischemical,PS_2 for western blotting and the contents of aninohexose and phosphatide in ulcerated gastric mucosa. RESULTS: The contents of aninohexose,phosphatide of PU patients increased in sea buckthorn procyanidins(SBPC) group.There was a linear correlation between the contents of phosphatide,aninohexose and the expression of ITF、PS_2 in PU patients(P
