Effect of peppermint oil on GSH and ATPase in rat liver-tissues and primary cultured rat hepatocyte
- VernacularTitle:薄荷油对大鼠肝组织GSH、ATP酶和原代肝细胞的影响
- Author:
Hongjie LIU
;
Ruomin JIN
;
Shuangyan QI
;
Caixia MEI
;
Liming TANG
- Publication Type:Journal Article
- Keywords:
peppermint oil;
rats;
liver damnification;
GSH;
ATPase
- From:
Chinese Traditional Patent Medicine
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the effect of peppermint oil on GSH、ATPase in rat liver-tissues and primary cultured rat hepatocyte. METHODS: The rat liver tissues were obtained to detect content of GSH and level of Na~+-K~+-ATPase、Ca~(2+)-Mg~(2+)-ATPase after being administered peppermint oil orally at 24 % concentration of peppermint oil in 36 and 48 hours.Primary rat hepatocyte was separated and cultured,then peppermint oil and the serum containing that were respectively added level of LDH,ALT,AST in the supernatant fluid was respectively determined after incubating for 12,24 and 48 hours. RESULTS: The content of GSH and level of Na~+-K~+-ATPase and Ca~(2+)-Mg~(2+)ATPase in liver tissues was low remarkably(P