Assessment of the Optimum LDL : HDL-cholesterol(LDL : HDL-C) Ratio for Predicting CHD.
- Author:
Soon Gyo YEOUM
1
Author Information
1. Department of Nursing, Seoil College, Korea. yeoumsg@seoil.ac.kr
- Publication Type:Original Article
- Keywords:
Coronary heart disease;
LDL;
HDL;
Cholesterol
- MeSH:
Adult;
Cholesterol;
Coronary Disease;
Female;
Heart;
Humans;
Lipoproteins;
Logistic Models;
Male;
Odds Ratio;
Risk Factors
- From:Journal of Korean Academy of Adult Nursing
2008;20(6):917-931
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study was aimed to determine the optimum low-density lipoprotein : high-density lipoprotein-cholesterol (LDL : HDL-C) ratio for predicting coronary heart disease(CHD) in Korean people. METHODS: It was analyzed this data of 5,431 adults who had undergone health examinations in a hospital in Gyeonggi-do between January 2006 and December 2007. The covariation of the coronary risk factors such as age, HbA1C, systolic blood pressure(SBP), and waist-to-stature ratio(WSR) were analyzed by using logistic regression analysis. RESULTS: The LDL : HDL-C ratio in the male and female groups was mostly distributed between 1.5 and 4.0. The LDL : HDL-C ratio was the most significant cholesterol-related parameter influencing CHD(male: B = .306, p = .054, female : B = .940, p = .010), followed by LDL-C and total cholesterol. It was observed a sharp increase in the odds ratios for LDL : HDL-C ratios of 2.25 - 2.50(male) and 2.00 - 2.25(female). A significant difference was observed in both male(2.25 : chi-square = 2.494, p = .072) and female(2.00 : chi-square = 413.742, p = .000) groups. CONCLUSION: The risk level of CHD was set to 2.25 for males and 2.00 for females. Therefore, the optimum LDL : HDL-C ratio for Koreans should be far lower than that for the people in western countries.
