Investigation of protective role of Shenfu injection in ischemia-reperfusion injury of transplanted livers in rats
- VernacularTitle:参附注射液对大鼠移植肝脏缺血再灌注损伤的保护作用
- Author:
Yibin ZHANG
- Publication Type:Journal Article
- Keywords:
SF injection;
Liver transplantation;
Ischemia-reperfusion injury
- From:
Journal of Chongqing Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the protective role of Shenfu injection(SF) in ischemia-reperfusion injury of transplanted livers in rats.Methods:48 male SD rats,weighted 200~230g,were selected and divided into control group and SF group at random.All of them were performed liver transplantation.2h,4h and 6h after the transplantation,they were analyzed for level of biliation,serum alanine aminotransferase,tumor necrosis factor-?(TNF-?),NF-?B expression in hepatic tissue and the morphological observation of hepatic tissue under light/electron microscope.Results:At each phase,biliation in SF group was significantly higher than in control group(P
