Purification of Acanthopanax root extract with anticerebral ischemia
- VernacularTitle:刺五加抗脑缺血作用物质基础纯化工艺优选
- Author:
Xiaobin TAN
- Publication Type:Journal Article
- Keywords:
Acanthopanax senticosus Harms;
syringin;
flavone;
cerbral ischemia-reperfusion
- From:
Chinese Traditional Patent Medicine
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To optimize the purification of Acanthopanax senticosus Harms root extract based on the rodent with anticerebral ischemia. METHODS:We identified the effect of D-101 macroporous resin adsorption,polyamide adsorption and n-butanol extraction on cerebral ischemia-reperfusion injure model rat and behead-mouth(opening) model mouse in the treatment of aqueous acanthopanax root extract. RESULTS:Aqueous acanthopanax root extract,which was purfied by using D-101 macroporous resin,had advantage over that were treated with polyamide adsorption and n-butanol extraction.Eleutheroside content in the root extract showed the positive correlation with anticerebral ischemia. CONCLUSION:D-101 macroporous resin adsorption is a good purification method for acanthopanax root extract.
