The effect of antenatal administration with dexamethasone on the concentrations of vitamin A in fetal rats
- VernacularTitle:产前地塞米松对胎鼠组织维生素A水平的影响
- Author:
Chunxiao FANG
- Publication Type:Journal Article
- Keywords:
Dexamethasone;
Vitamin A concentrations;
Fetal rat;
Lung development
- From:
Journal of Chongqing Medical University
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effect of antenatal administration with Dexamethasone (Dex) on the vitamin A concentrations of tissues in fetal rats.Methods:Twelve pregnant Sprague-Dawley (SD) rats were randomly divided into 2 groups,one was Dex group,the other was control group.From the gestational day 16 to 18,the rats of the two groups were given Dex and Saline by intramuscular injectionrespectively.On gestational day 19,fetal rats were obtained by cesarean section,then the vitamin A concentrations of tissues (lung,liver) were detected by high-performance liquid chromatography(HPLC).Results:(1)Compared with the two groups,the per unit vitamin A concentrations of lung and liver in Dex group were higher than those of the control groop(P
