Protective Effect of Tongsaimai Pellets and Butylphthalide to PC12 Cell in Hypoxia/Hypoglycemia Model
- VernacularTitle:通塞脉微丸和丁基苯酞对PC12细胞缺氧缺糖损伤模型的保护作用
- Author:
Jin CHENG
;
Liuqing DI
;
Xiaoli ZHAO
- Publication Type:Journal Article
- Keywords:
Tongsaimai pellets;
butylphthalide;
PC12 cell;
hypoxia model;
hypoglycemia model
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the protective effect of Tongsaimai pellets(TSMP) and butylphthalide(NBP) on PC12 cell in the hypoxia/hypoglycemia model.Methods Two ischemia models including hypoxia,hypoglycemia models were used to assay the anti-ischemic roles of TSMP and NBP in cultured PC12.Results TSMP and NBP possessed obvious protective effects on PC12 cells from two injured models.Both of them could increase the number of living cells and decrease LDH activity significantly,particularly in hypoglycemia injured model.Conclusion TSM and NBP have protective effect on PC12 cells from two injured models effectively in vitro.
