Clinicopathologic study of epithelioid sarcoma
- VernacularTitle:上皮样肉瘤的临床病理研究
- Author:
Dan LI
- Publication Type:Journal Article
- Keywords:
Epithelioid sarcoma;
Diagnosis;
Differential diagnosis;
Prognosis
- From:
Journal of Chongqing Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the clinicopathologic features、diagnosis and differential diagnosis of epithelioid sarcoma.Methods:Two cases of epithelioid sarcoma were collected according to the classification of soft tissue and bone tumors(WHO,2002) and were studied by hematoxylin-eosin and immunohistochemical staining.Results:One case was proximal type epithelioid sarcoma,and the other distal type epithelioid sarcoma.The case of distal type epithelioid sarcoma was female,twenty eight years old,and the site was the left leg;histological structure was the typical pseudo-granuloma formation,the tumor cells resembled epithelioid cells,with necrosis in the center.The case of proximal type epithelioid sarcoma was female,thirty six years old,and the site was the cervix;nodal formation can be observed,the tumor cells resembled spindle cells,abd the extent of necrosis was bigger.For the immunohistochemical staining,expressions of Vimentin、EMA and CK antigen were observed in the 2 cases,while expressions of Desmin、NSE and S-100 antigen were negative.Moreover,expressions of low CK and CD34 antigen were also observed in the case of distal type epithelioid sarcoma.On the other hand,expressions of Actin、SMA and HMB-45 antigen were not observed in the case of proximal type epithelioid sarcoma.Conclusions:Epithelioid sarcoma is a rare maliglant tumor of soft tissue,It's the key for diagnosis and differential diagnosis to combine clinic、histological structure、immunophenotype and prognosis together.
