Determination of Strychnine in Cidan Capsules by HPLC
- VernacularTitle:HPLC测定慈丹胶囊中士的宁的含量
- Author:
Zhufeng CONG
;
Peng GAO
;
Shengjiang FU
- Publication Type:Journal Article
- Keywords:
Cidan Capsules;
Strychnine;
HPLC
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a HPLC method for the determination of strychnine content in Cidan Capsules. Methods Using Hypersil- C18 as the column and 1 % Acetic acid-acetonitrile (88 ∶ 12) as the mobile phase, HPLC was performed. The detection wavelength was 254 nm. Results The linear range was 0.112～ 0.560 ? g(r=0.999 9). The average recovery rate was 97.36 % , RSD was 1.00 % ( n=5) . Conclusion This method is accurate and specific.
