Effect of Weiyanyin on Substance P Content in Gastric Mucosa of Experimental Bile Reflux Gastritis Rats
- VernacularTitle:胃炎饮对胆汁反流性胃炎大鼠胃黏膜P物质含量的影响
- Author:
Muxiang YANG
;
Wentao YU
;
Shaoning ZHAO
;
Xiaowen LIU
;
Jianwei LIU
- Publication Type:Journal Article
- Keywords:
Weiyanyin;
Experimental bile reflux gastritis;
Substance P
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Weiyanyin on Substance P(SP) in gastric mucosa of experiment bile reflux gastritis rats. Methods The model of experiment bile reflux gastritis was established by gavage of reflux liquid. Compared with Domperidone, the effect of Weiyanyin on pathological histological features and the mucosal SP content of bile reflux gastritis rats was observed. Results The gastric mucosa of rats in model group was damaged, and alopecia of gastric mucosa, and infiltration of a large number of inflammatory cells could be seen.In most of the rats in the model group, atypical hyperplasia and intestinal metaplasia were present. Meanwhile, the content of SP was decreased( P
