Experimental Study on Effect of Xin Guanxin Suhe Drop Pill on Acute Myocardial Ischemia
- VernacularTitle:新冠心苏合滴丸抗大鼠急性心肌缺血的实验研究
- Author:
Chunxiang LI
;
Liyu DING
;
Qing LI
;
Xiaohui ZHU
;
Fang DING
;
Lei HAO
- Publication Type:Journal Article
- Keywords:
Xin Guanxin Suhe Drop Pill;
Myocardial ischemia;
Isoprenaline
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Xin Guanxin Suhe Drop Pill(XGSDP) on isoprenaline (ISO)-induced acute myocardial ischemia (AMI).Methods Acute myocardial ischemia rats model were established by injection of ISO. Electrocardiogram (ECG) was observed, superoxide dismutase(SOD) activity, and the contents of malondialdehyde(MDA) and nitric oxide (NO) in the myocardial homogenate as well as serum and glutamate oxaloacetate transaminase (GOT) were observed after ISO injection. Results XGSDP could significantly increase NO content and SOD activity, decrease contents of MDA and GOT and reduce the positive rate of ECG( P
