Process of Guanxinning for Injection purified with macroporous adsorption resin
- VernacularTitle:大孔吸附树脂纯化注射用冠心宁的工艺研究
- Author:
Hanbin WANG
;
Jian XUE
;
Hangping CHEN
;
Zhixin SUO
;
Dingkai YU
- Publication Type:Journal Article
- Keywords:
marcroporous adsorption resin;
Guanxinning;
technical study
- From:
Chinese Traditional Patent Medicine
1992;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To study the purified factors of Guanxinning for Injection(Radix et Rhizoma salviae miltiorrhizae,Rhizoma Chuanxiong,etc). METHODS: The total of salvianolic acid B、protocatchuci aldehyde and ferulic acid were used to evaluate for the study of type of macroporous adsorption resin,sample volume,the ratio of diameter to height,pH value and sample consistency etc. RESULTS: pH value Guanxinning extract was adjusted to 3.0,through D101 resin finally reached the ratio of diameter to height 1∶2,4 times of water was applied to elution and then 3 times of 70% ethanol for re-elution and collected. CONCLUSION: These factors are approprite for purifying Guanxinning for Injection.