The preparation of matrine sustained-release tablet and the determination of its dissolution rate
- VernacularTitle:苦参碱缓释片的制备及释放度研究
- Author:
Xianzhong HAN
;
Xin LIU
;
Jin NIE
;
Xiaotai FU
;
Shurong JIN
;
Weiming YU
- Publication Type:Journal Article
- Keywords:
matrine;
sustained-release tablet;
preparation;
release rates
- From:
Chinese Traditional Patent Medicine
1992;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To prepare sustained release matrine tablet,and study its drug release test in vitro. METHODS: In combination with HPLC,we studied the cumulative matrine release using HPLC and EC as the sustained materials. RESULTS: The release of matrine was conformed to Higuchi equation. CONCLUSION: The drug release behavior could be well described in vitro,and meet the design criteria,it is easy to be produced.
