Experimental Study of Shufeng Decoction on Resisting Type I Hypersensitivity
- VernacularTitle:疏风饮抗I型超敏反应实验研究
- Author:
Xing CHEN
;
Hongquan GUAN
- Publication Type:Journal Article
- Keywords:
Shufeng Decoction;
type I hypersensitivity;
IL-4;
IFN-?;
IgE;
rat
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects and mechanism of Shufeng Decoction resisting type I hypersensitivity. Methods Type I hypersensitivity was induced by OVA. The content of IL-4, IFN-? and IgE in serum of the rats treated by Shufeng Decoction were determined by ELISA. Results Shufeng Decoction can increase the content of IFN-? in model rats (P0.05). IFN-?/IL-4 of Shufeng Decoction was significant higher than model group (P0.05). Conclusion The effects and mechanism of Shufeng Decoction on prophylaxis and treatment of type I hypersensitivity of skin (acute urticaria) may be related with regulating cell factors and influencing the balance of Th1/Th2.
