Comparative experimental study on urethral scar following hypospadiac repair
- VernacularTitle:尿道下裂术后尿道瘢痕的对比实验研究
- Author:
Xing LIU
- Publication Type:Journal Article
- Keywords:
Hypospadias;
Scar;
Urethral stricture;
Surgical procedure
- From:
Journal of Chongqing Medical University
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare characters of urethral healing after different surgical procedures to provide theoretical support for preventing and curing urethral scaring stricture after hypospadias repair.Methods:Hypospadiac animal model was established and three surgical procedures were adopted to repair urethra.The dynamic changes of urethral healing and scar were observed,the expressions of ?-SMactin and TGF-?1 were examined.Results:Mathieu and Onlay island flap(Onlay) had notable collagenous proliferation,which was significantly stronger than that of Tubularized Incised Plate urethroplasty(TIPU)(P
