Expression of PTEN in endometrial carcinoma and its clinical significance
- VernacularTitle:PTEN在子宫内膜样腺癌中的表达及其临床意义
- Author:
Qin ZHOU
- Publication Type:Journal Article
- Keywords:
PTEN;
Endometrial carcinoma;
Immunohistochemical method
- From:
Journal of Chongqing Medical University
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objectives:To study the expression of PTEN in endometrial carcinoma under different pathological factors and to discuss its relationshipwith the occurrence of endometrial carcinoma and the clinical significance.Methods:The expressions of PTEN in 40 cases of endometrial carcinoma,10 cases of atypical hyperplasia and 10 cases of normal endometria were examined by immunohistochemical method.Result:The positive staining rate of PTEN in endometrial carcinoma was 55.00%,and that in normal endometria was 100.00%.There was no obvious correlation between the expression of PTEN in endometrial carcinoma and different pathological factors such as clinical staging,depth of myometrial invasion and lymph node metastasis.Conclusion:The expression lack of PTEN exists in endometrial carcinoma,and PTEN has an important role in the occurrence of endometrial carcinoma.
