Clinic study of fresh amniotic membrane transplantation for ocular surface reconstruction
- VernacularTitle:新鲜羊膜移植重建急性烧伤眼表的临床研究
- Author:
Xin NIE
- Publication Type:Journal Article
- Keywords:
Amniotic membrane;
Transplantation;
Eye burn;
Surgery
- From:
Journal of Chongqing Medical University
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the possibility of fresh amniotic membrane transplantation for reconstruction of ocular surface with acute burn and evaluate the effect.Method:20 cases(24 eyes)due to acute burn of ocular surface were performed fresh amniotic membrane transplantation.All patients were followed up for 12 months to 26 months,the mean follow-up was(15?2)months.Visual acuity,epithelial healing,corneal transparency,corneal neovascularization and transplanted amniotic membrane were observed.Results:After fresh amniotic membrane transplantation,ocular surface was soon stable,immune rejection and secondary infection didn't occur.In 19 of 20 cases(23 eyes) the amniotic membrane autolyzed or disappeared with epithelized corneal surface at 14 to 28 days after operation.In one case(one eye) autolyzed corneal ulcer occurred at 12 days after operation.After another medication treatment was invalid,lamellar keratoplasty was performed.In other cases with AMT visual acuity keeps CF/5cm.Conclusion:Fresh amniotic membrane transplantation can lighten corneal inflammation in acute course of burn,can prevent ocular surface from ulcer and deliquescion,can fasten the stabilization and reduce corneal neovascularization,which provide a good basis for the following keratoplasty.With regard to severe eye burn,the effect of AMT is limited.
