Clinical effect of Fuzheng Jiedu Granule combined with western medicine on 60 patients with coronary heart disease long-term exposed to nickel
- VernacularTitle:扶正解毒颗粒与西药结合治疗60例长期接触镍的冠心病患者的临床研究
- Author:
Zitai WEI
;
Jianxiong ZHAO
- Publication Type:Journal Article
- Keywords:
nickel;
coronary heart disease;
enzyme;
Fuzheng Jiedu Granule
- From:
Chinese Traditional Patent Medicine
1992;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To evaluate the clinical effect of Fuzheng Jiedu Granule(Radix Hedysari,Poria,Radix Angelicae sinensis,Fructus Forsythiae,Rhizoma Curcumae,Radix et Rhizoma Salviae miltiorrhizae,etc.) on patients with coronary heart disease who have longterm contact with nickel,and observe its influence on the level of Creatine kinase(CK),Lactate dehydrogenase(LDH),Na~+-K~+-ATPase,Ca~(2+)-ATPase in RBC membrane,Nitric oxide(NO),Nitric oxide synthase(NOS),Nickel(Ni) in serum. METHODS: 60 cases were divided into two groups A and B randomly.30 cases in group A were treated with Fuzheng Jiedu Granule combined with western medicine Betaloc and Isosorbide Dinirrate;30 cases in group B were given only western medicine.The period of treatment was 4 weeks.Another 15 healthy cases selected as group C(healthy control group).Before and after treatment,the clinical effects were observed,meanwhile,some biochemical indexes such as CK,LDH,Na~+-K~+-ATPase,Ca~(2+)-ATPase in RBC membrane,NO,NOS,Ni in serum were measured with clinic test methods.Finally,the experimental results were compared and analyzed in the three groups mentioned above. RESULTS: The therapeutic effect of symptoms and signs of group A was superior to that of group B(P
