Determination of chlorogenic acid、paracetmol、Vitamin C and chlorphenamine maleate in Vitamin C Yinqiao Tablets by HPLC
- VernacularTitle:HPLC同时测定维C银翘片中绿原酸、对乙酰氨基酚、维生素C、马来酸氯苯那敏的含量
- Author:
Guangwei GAO
;
Xiangdong FENG
;
Haixin HUANG
- Publication Type:Journal Article
- Keywords:
Vitamin C Yinqiao Tablets;
chlorogenic acid;
paracetmol;
Vitamin C;
chlorphenamine maleate;
HPLC
- From:
Chinese Traditional Patent Medicine
1992;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To establish a method of determining the content of chlorogenic acid,paracetmol,vitamin C and chlorphenamine maleate in Vitamin C Yinqiao Tablets. METHODS: The separation was performed in the C_(18) colunm with the mobile phase of methanol-acetonitril-0.02% phosphate acid(5∶10∶85).The flow rate was(1.0 mL/min) with the wavelength at 219 nm and 310 nm,the temperature of column was 35 ℃. RESULTS: The calibration curves were linear in the ranges of 0.03-0.13 ?g for chlorogenic acid,0.94-4.68 ?g for paracetmol,0.49-2.44 ?g for Vitamin C,0.01-0.05 ?g for chlorphenamine maleate,the average recoveries were not less than 98%,respectively. CONCLUSION: The method is simple,rapid and with satisfactory results.It is suitable for quality control of Vitamin C Yinqiao Tablets.
