Preparation of ?-elemene solid lipid nanoparticles by film-ultrasonic wave dissolving techniques
- VernacularTitle:薄膜-超声分散法制备?-榄香烯固体脂质纳米粒
- Author:
Hongmei LIU
;
Huiyuan CHU
;
Jinxia CUI
;
Linhua WU
- Publication Type:Journal Article
- Keywords:
?-elemene solid lipid nanoparticles;
film-ultrasonic wave dissolving technique;
preparing
- From:
Chinese Traditional and Herbal Drugs
1994;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To prepare ?-elemene solid lipid nanoparticles and investigate their particle size diameter and entrapment efficiency.Methods The ?-elemene solid lipid nanoparticles were prepared by film ultrasonic wave dissolving techniques.And the optimum formula was selected through orthogonal design test according to the entrapment efficiency.Results The optimizing technique was ?-elemene(20 ?L),stearic acid(90 mg),lecithin(90 mg),Tween80(2.5 %,5 mL) and Poloxamer 188(2.5 %,5 mL).Conclusion The technique of preparing ?-elemene by film-ultrasonic wave dissolving technique is feasible.
