EFFECT AND POSSIBLE MECHANISMS OF PANAXYDOL ON NTFs EXPRESSION IN SCHWANN CELLS IN VITRO
- VernacularTitle:人参环氧炔醇对体外培养施万细胞表达神经营养因子的影响及可能机制的研究
- Author:
Jing HE
;
Wenlong DING
- Publication Type:Journal Article
- Keywords:
Schwann cells;
Panaxydol;
Neurotrophic factors;
cAMP;
Immunohistochemistry;
Radioimmunology;
Rat
- From:
Acta Anatomica Sinica
1953;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of panaxydol(PND) upon neurotrophic factors(NTFs) expression in Schwann cell,and to further reveal the mechanisms that underlie these effects. Methods Schwann cells were treated with PND of different concentrations in the culture medium.NTFs expression was examined through immunoiistochemistry assay.The intracellular cAMP level was assessed by radioimmunologic assay. Results There was an increase in NGF expression after PND treatment within the range of 2.5-20.0?mol/L(P
