Effect of Kuijieling Granules on Toll-like Receptor and Other Indexs in the Patient of Ulcerative Colitis of Damp Heat in the Large Intestine Stagnation Type
- VernacularTitle:溃结灵颗粒对大肠湿热型溃疡性结肠炎患者Toll-like受体等指标的影响
- Author:
Dong CHANG
;
Zhixin HUANG
;
Yawei FAN
- Publication Type:Journal Article
- Keywords:
ulcerative colitis;
Kuijieling Granules;
Toll-like receptor
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect and study intervenient action of Kuijieling Granules (KG) in treating ulcerative colitis (UC) during the active period by the clinical experiment. Methods The patients of active UC (damp-heat syndrome) were randomly divided into 2 groups (KG+SASP group and SASP group) to observe pathological changes of the mucosa,syndrome effect and main symptoms scores,and the protein expression of TLR4,CD14 and NF-?B p65 were detected by immunohistochemistry. Results KG+SASP group had better effect than SASP group in syndrome and mucosa (P0.05). There were outstanding differences among the pathologic grade of UC about IA of TLR4,CD14 and NF-?B p65. The expression of TLR4,CD14 and NF-?B p65 were decreased by treatment (P
