Study on the biocompatibility of semiconductor quantum dots to the rat dental papillae cells (RDPC) cultured in vitro
- VernacularTitle:半导体量子点对原代培养大鼠牙乳头细胞生物相容性的研究
- Author:
Deping SUN
- Publication Type:Journal Article
- Keywords:
Semiconductor quantum dots (semiconductor nanoerystals);
Rat dental papillae cells(RDPCs);
Biocompatibility;
Oral cavity;
Live cells
- From:
Journal of Chongqing Medical University
2007;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the biocompatibility of semiconductor quantum dots to the rat dental papillae cells(RDPCs) cultured in vitro. Methods:①RDPCs isolated and cultured with enzyme digestion. Wave form fibroin and cytokeratin were used to identify the cells resource and the growth rules of cells was observed.②To study the effeel of QDs to the RDPCs,The RDPCs were cultured with the 605QDs,525QDs and those mixture in different density.③With the MTT, to studv the cytotoxicity of QDs to the RDPCs,The RDPCs were cultured with the 605QDs,525QDs and those mixture in different density. Results:①RDPCs cultured in vitro were well growing. Wave form fibroin staining was positive and cytokeratin staining was negative in RDPCs.②The 605QDs,525QDs and those mixture in different density show no negative effect and cytotoxicity on the growth of the RDPCs. Conclusion:The 6050Ds、525QDs in a range of density have well biocmpatibility to the live cells,which supplied scientific evidence for the research of multichannel signal in living cells in vivo physiological condition
